Hi: I noted the recent posting of an abstract on dopamine and ginko biloba. I also saw this abstract.
From the Reuniting page:
I also spotted a previous report that seems to contradict this paper, that which that gingko biloba "upregulates" prolactin in the cerebral cortex of rats (hmmm ... does this apply to humans).
From the paper cited in Reuniting: "After treatment for 28 days, no significant difference was seen in mount latency, intromission latency, serum T levels, reproductive organ weight, sperm number, or levels of the metabolite of dopamine, 3,4-dihydroxyphenylacetic acid in the brain with any dose of EGb 761, but significantly reduced serum prolactin levels and increased dopamine levels in the medial preoptic area and arcuate nucleus were seen at the dose of 50 mg/kg. "
Ginkgo biloba extract enhances male copulatory behavior and reduces serum prolactin levels in rats
Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.
Yeh KY, Pu HF, Kaphle K, Lin SF, Wu LS, Lin JH, Tsai YF.
Horm Behav. 2008 Jan;53(1):225-31. Epub 2007 Oct 10.
But ... from a paper published in 2001:
"The expression [induced by gingko extracts] of a-amino-3-
hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-2, calcium
and chloride channels, prolactin, and growth hormone (GH), all of
which are associated with brain function, were also up-regulated"
The in vivo neuromodulatory effects of the herbal medicine ginkgo biloba
Coran M. H. Watanabe*, Siegfried Wolffram†, Peter Ader†, Gerald Rimbach‡, Lester Packer§, John J. Maguire¶,
Peter G. Schultz*i, and Kishorchandra Gohil**
Can anyone comment? One seems to say that gingko raises prolactin, the other seems to say gingko decreases it.