The science behind the sexual hangover

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http://www.reuniting.info/science/articles/acute_dopamine_depletion_caus...

This new research shows that drops in dopamine can cause psychological symptoms. Although the drops were created with drugs, not with sexual satiation, but same dopamine receptors are affected in each case.

It's easy to see how such feelings could be projected onto a partner, and could create emotional separation in an intimate relationship.